Safe-formula - 5842

Teagasc project team: Prof. Paul Ross (PI), Catherine Stanton, Caitriona Guinane, Robert Kent Project dates: Jan 08 – Sept 2011

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Main results:

• An enzymatic method has been developed to release the antimicrobial peptide Caseicin A (IKHQGLPQE) from casein, based on hydrolysis with the commercial enzyme Thermoase PC10F.
• A second antimicrobial peptide (VFGKEKVNE) was identified in the casein hydrolysate.
• Food trials with Thermoase PC10F hydrolysates demonstrated a significant reduction in pathogen growth compared to controls.