Emmanuel Kuffour Osei
Postdoctoral Fellow - MicrobiologyResearch Interests
Emmanuel Kuffour Osei is a Postdoctoral Fellow whose research areas include antimicrobial resistance and bacteriophage (phage) therapy, microbial genomics, viromics, probiotics, pig health, early-life nutrition and the gut–brain axis. He combines omics technologies, high-throughput in vitro screening, and animal and human studies to investigate microbial communities and their impact on health. His work integrates metagenomics, metabolomics and dietary data to understand host–microbe interactions and identify microbiome-targeted interventions. He is currently working on the MAEVE project, investigating how dietary polyphenols influence the gut microbiome, microbial metabolites, and brain and cognitive health in individuals at increased risk of Alzheimer’s disease.
Current Projects
MAEVE: Microbiota mediated flavonoid metabolites for cognitive health
PhageSUAS: “Improved Pig Health through the Novel Application of SynBio in Phage Therapy”
Education
PhD. University College Cork, Ireland
MSc. University of Leicester, UK
Professional Membership
Microbiology Society
International Society for Viruses of Microorganisms
View publications by Emmanuel Kuffour Osei on Google Scholar
- Thanki AM, Osei EK, Whenham N, Salter MG, Bedford MR, Masey O’Neill HV, Clokie MRJ.2024.Broad host range phages target global Clostridium perfringens bacterial strains and clear infection in five-strain model systems. Microbiol Spectr12:e03784-23. https://doi.org/10.1128/spectrum.03784-23
- Osei, E. K., Mahony, J., & Kenny, J. G. (2022). From Farm to Fork: Streptococcus suis as a Model for the Development of Novel Phage-Based Biocontrol Agents. Viruses, 14(9), 1996. https://doi.org/10.3390/v14091996
- Osei, E. K., O’Hea, R., Cambillau, C., Athalye, A., Hille, F., Franz, C. M. A. P., O’Doherty, Á., Wilson, M., Murray, G. G. R., Weinert, L. A., Garcia Manzanilla, E., Mahony, J., & Kenny, J. G. (2025). Isolation of phages infecting the zoonotic pathogen Streptococcus suis reveals novel structural and genomic characteristics. Microbiological Research, 296, 128147. https://doi.org/10.1016/j.micres.2025.128147
- Osei, E. K., O’Mahony, A. K., O’Hea, R., Moriarty, J., O’Doherty, Á., Wilson, M., Garcia Manzanilla, E., Mahony, J., & Kenny, J. G. (2026). Genomics of Irish swine-derived Streptococcus suis: Population structure, prophages and anti-viral defence mechanisms. Microbial Genomics, 12(1), 001590. https://doi.org/10.1099/mgen.0.001590
- Okuofu, S. I*., Osei, E. K*., Leech, J., Kenny, J. G., O’Flaherty, V., & McAuliffe, O. (2026). Comparative genomic analysis of poly-γ-glutamic acid producing Bacillus licheniformis strains isolated from dairy products. Journal of Genetic Engineering and Biotechnology, 24(2), 100682. https://doi.org/10.1016/j.jgeb.2026.100682