Joseph Ancla

Project Title: Metagenomics Analysis of the Human Gut Virome: Effects of Milk Kefir Consumption in a Cohort of Healthy Individuals and those with Metabolic Syndrome

Overview: Joseph is a PhD scholar at Teagasc Moorepark conducting research on the impact of milk kefir consumption on the human gut virome in healthy individuals and those with metabolic syndrome. Utilizing viromics analysis, the study aims to explore the effects of milk kefir on the adaptation, diversity, interaction networks, and functions of viruses, particularly phageome (the community of bacteriophages) within the gut microbiome. By investigating the correlation between the gut microbiome and healthy and diseased populations, the study seeks to elucidate the essential role of viruses in maintaining a healthy and stable human gut. This research is a component of the EU-funded project DOMINO, which endeavors to elucidate the impact of fermented food consumption on the gut microbiome and its associated health benefits for consumers.

Joseph holds a Bachelor of Science in Medical Technology and has extensive experience in bacteriology, virology, and molecular biology. Previously, he was involved in a research project that explored the potential synergistic application of bacteriophages’ lytic activity and plant extracts’ antimicrobial properties in combating multidrug-resistant bacteria, with a specific focus on the ESKAPE microorganisms.

Programme Area: Food Biosciences

Supervisors: Dr Orla O’Sullivan, Dr John Kenny, Prof Paul Cotter and Prof Andrey Shkoporov

Location: Teagasc Food Research Centre, Moorepark

Funding Source: Teagasc